Fatty acids affected key signalling pathways responsible for development of mental illness.

Obesity has been linked to depression by scientists for years, but the reasons have always been somewhat unclear until now.

New research led by the University of Glasgow has found that the connection might be down to dietary fats entering the brain through the bloodstream, which can then accumulate and affect neurological signals related to depression.

The study, published in the journal Translational Psychiatry on Friday, was conducted on mice that were fed fat-dense diets.

The researchers said that after close observation, they noted the saturated fatty acids enter into the brains of the mice in their hypothalamus region, which is related to the metabolic system and is known to be linked to depression.

The fatty acids then affected key signalling pathways that are known to be responsible for the development of the mental illness. Obesity has been linked to depression by scientists for years, but the reasons have always been somewhat unclear until now.

New research led by the University of Glasgow has found that the connection might be down to dietary fats entering the brain through the bloodstream, which can then accumulate and affect neurological signals related to depression.

The study, published in the journal Translational Psychiatry on Friday, was conducted on mice that were fed fat-dense diets.

https://www.independent.co.uk/life-style/obesity-depression-mental-health-study-dietary-fats-brain-a8907826.html